Abraham Z. Snyder, Ph.D., M.D.

DEPARTMENT OF Radiology
Keywords: MRI, PET, validation, algorithms

Dr. Snyder’s work consists principally of applied image processing, especially in connection with functional neuroimaging. Ongoing projects involve functional and structural magnetic resonance imaging (fMRI and MRI) as well as metabolic and receptor imaging using positron emission tomography (PET). This work requires development, maintenance and application of algorithms for image registration, image averaging, intensity inhomogeneity correction, and image segmentation. Typical applications include correction for intra-acquisition head motion, coregistration of multi-spectral (including functional) datasets in the same individual, representation of functional responses on the smoothed or flattened cortical surface and generation of atlas representative target images for averaging over multiple individuals. Other applications include diffusion tensor imaging (DTI) and DTI-tractography.

Specific active areas of investigation include the following:
- White matter abnormalities in aging and dementia.
- Validation of DTI-tractography using retinotopy in humans.
- fMRI studies of cortical reorganization consequent to blindness.
- fMRI studies of the perception of bizarreness.
- Creation of age-appropriate atlas representative images for use in children.